The ASUS Sabertooth P67 is clearly targeted to the user concerned with quality and reliability. If you want to build a system that will last years without giving you trouble, this is a motherboard to consider.
Additionally, if you are concerned with heat, the Sabertooth P67 provides a thermal cover that avoids hot air coming from the CPU cooler and the video cards to heat the motherboard components, you can add a small 50 mm fan to cool them down, and the motherboard can adjust the speed of the fans connected to the board depending on the temperature of key components.
The features available, such as four SATA-600 ports, four USB 3.0 ports, two PCI Express x16 slots, two eSATA-300 ports, two FireWire ports, and on-board SPDIF output, will satisfy the demanding user. It is important, however, to understand that the Sabertooth P67 is not a “true” high-end model. Extreme enthusiasts will require more overclocking options, more PCI Express x16 slots, and a better audio codec, just to name a few of the features that are “missing.”